The primary use of PVR (Protein Volume Replacer) is for hypoproteinemia or hypovolemic critical care patients pre- and post-operatively where protein has been lost from the intravascular space due to a decrease of oncotic pressure. The intravascular oncotic pressure is maintained, principally by albumin (which is responsible for 75% of the oncotic pressure of the plasma) and with contributions from globulin and fribrinogen. The macro components of ImmunoGlo™ PVR are albumin, immunoglobulins, fibrin (clotting factors) with the remainder made up of other proteins and protein factors (factors XII, XI, IX, X, V, VII, II, I, and VIII). ImmunoGlo PVR is rich in clotting factors, albumin, and globulins essential for carrying necessary proteins to bodily tissues during trauma situations. Administration of PVR replenishes the ability to move medication, signal hormones, water, enzymes, and other molecules deeper into tissue during high-stress situations. This is particularly helpful in transporting antibiotics and pharmaceuticals further into the tissue, helping them work faster.