TERRAMYCIN® Ophthalmic Ointment with Polymyxin B Sulfate is indicated in dogs and cats with superficial ocular infections, such as conjunctivitis, keratitis, pink eye, corneal ulcer, blepharitis and bacterial inflammatory conditions that may occur secondary to other infectious diseases. In dogs, it is also indicated for ocular infections due to secondary bacterial complications of distemper. Broad-spectrum effectiveness against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa. The combined antibacterial effect of oxytetracycline hydrochloride and polymyxin B is at least additive, and in many instances, an actual synergistic action occurs.