Neo-Predef with Tetracaine Topical Powder is indicated in the treatment or adjunctive therapy of certain ear and skin conditions—in dogs, cats and horses—caused by or associated with neomycin-susceptible organisms and/or allergy. In addition, it is indicated as superficial dressing applied to minor cuts, wounds, lacerations and abrasions, and for postsurgical application where reduction of pain and inflammatory response is deemed desirable. Neo-Predef with Tetracaine may be used as a dusting powder following: amputation of tails, claws and dew-claws; ear trimming and castrating; and surgical procedures such as ovariohysterectomies. Applied superficially, it has been used successfully in the treatment of acute otitis externa, acute moist dermatitis and interdigitial dermatitis in dogs, and as a dusting powder to various minor cuts, lacerations, and abrasions in the horse, cat and dog.